Skin Sensitizer A substance that will induce an allergic response following skin contact. The definition for "skin sensitizer" is equivalent to "contact sensitizer".

Greet Teuns, in Nonclinical Assessment of Abuse Potential for New Pharmaceuticals, 2015. 2.3 Sensitization. Sensitization (the opposite of tolerance) to active substances is defined as an increased effect of the substance following repeated doses. In particular, behavioral sensitization or psychomotor sensitization can be observed in animals treated with stimulants, as evidenced by enhanced

Blister package: A cavity is made in a thermoformed plastic, the drug in the form of a tablet or capsule is kept in the cavity, and it is sealed on the open side with plastic or aluminum foil. Google Scholar provides a simple way to broadly search for scholarly literature. Search across a wide variety of disciplines and sources: articles, theses, books, abstracts and court opinions. Links to industry guidance, forms and inventories for food packaging and food contact substances. 2013-01-10 · 1.

Sensitiser mean on the packaging of a substance

Introduction. Identification or categorization of sensitizing chemicals to skin is an important process in chemical risk assessment. Current classifications of skin sensitizers have mostly been achieved using the mouse local lymph node assay (LLNA) and guinea pig tests, including the Buehler test or guinea pig maximization test (GPMT) (Kimber et al., 1995, Kimber and Weisenberger, 1989 What does PTNSR mean? PTNSR as abbreviation means "Packaging and Transport of Nuclear Substances Regulations". Q: A: What is shorthand of Packaging and Transport of Nuclear Substances Regulations? The most common shorthand of "Packaging and Transport of Nuclear Substances Regulations" is PTNSR.

CONSIDERATIONS 3.

1.0 CATEGORY DEFINITION AND ITS MEMBERS The substances within this category consisting of rosin, hydrogenated rosin and mono classified according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regu

Meaning: (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction. 9. If you see the word “SENSITISER” on a bottled substance, this means that____ .

Substances can be classified as skin sensitisers if there is evidence from experimental tests or in humans that the substance can lead to sensitisation by skin contact. From information in the Classification and Labelling Inventory, there are over 14 000 substances on the EU market with some indication of a skin sensitising concern.

The noun SENSITISER has 1 sense: 1. (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction.

Sensitiser mean on the packaging of a substance

av A Julander · Citerat av 2 — classification, labelling and packaging of substances and mixtures. DFG. Deutsche Occupational skin diseases represent up to 30% of the occupational diseases in. Europe. Repeated exposure to the sensitiser, impaired skin barrier like in Given the special risks that substances classifiedas carcinogenic, mutagenic or toxic for packaging andlabelling of dangerous substances (2), may entail for human or toxic for reproduction categories 1, 2 or 3, or as a respiratory sensitiser. including such use by reproduction in copies or audio or by any other means, Given the special risks that substances classifiedas carcinogenic, mutagenic or toxic packaging andlabelling of dangerous substances (2), may entail for human within the meaning of Directive 2006/115/EC of the European Parliament and of or toxic for reproduction categories 1, 2 or 3, or as a respiratory sensitiser. Can a company wishing to provide information for substances and mixtures for which an SDS is not required, use the SDS format? Yes, the SDS format can be In terms of skin sensitization potency, the rate to assign a substance to the next vehicle” analysis, on average in 9.3% of the cases a less severe been categorized as a strong/moderate sensitiser (Basketter et al., 2014) and was Labelling and Packaging (UN GHS/EU CLP) classification for serious eye “Allergy” comes from the ancient Greek words allos meaning “other” and ergon contact sensitiser or exposure to a possible cross-reacting substance, at a aluminium―which, for example, is used in transport, packaging, I denna definition avses med ”monomerenhet” packaging of substances and mixtures, amending and repealing Directives 67/548/EEC unless the preparation is already classified and labelled as a sensitiser with.
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DFG. Deutsche Occupational skin diseases represent up to 30% of the occupational diseases in. Europe. Repeated exposure to the sensitiser, impaired skin barrier like in Given the special risks that substances classifiedas carcinogenic, mutagenic or toxic for packaging andlabelling of dangerous substances (2), may entail for human or toxic for reproduction categories 1, 2 or 3, or as a respiratory sensitiser. including such use by reproduction in copies or audio or by any other means, Given the special risks that substances classifiedas carcinogenic, mutagenic or toxic packaging andlabelling of dangerous substances (2), may entail for human within the meaning of Directive 2006/115/EC of the European Parliament and of or toxic for reproduction categories 1, 2 or 3, or as a respiratory sensitiser. Can a company wishing to provide information for substances and mixtures for which an SDS is not required, use the SDS format?

In urgent cases, please submit your question through the contact form.You can also call the ECHA Switchboard: +358 9 6861 80. The process by which your body becomes sensitive to—and allergic to—a particular substance is called sensitization. When your immune system becomes sensitized to an allergen (an otherwise harmless substance), you will likely develop symptoms of an allergy each time you are exposed to that same allergen. – UN Globally Harmonised System for Classification, labelling and packaging (GHS/CLP) – REACH – Cosmetics Directive Info traditionally obtained with animal tests – Guinea pig tests, Local Lymph Node Assay (LLNA) Information on potency if a substance is a skin sensitiser often required – Intrinsic strenght to induce sensitisation Substances known to cause cancer are called carcinogens.
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It establishes the set of criteria to which a drug substance or drug product should conform to be considered acceptable for its intended use. "Conformance to specifications" means that the drug substance and / or drug product, when tested according to the listed analytical procedures, will meet the listed acceptance criteria.

In contrast to respiratory irritation, respiratory sensitization is an immunological response to previous exposure to a chemical. A substance that will induce an allergic response following skin contact. The definition for "skin sensitizer" is equivalent to "contact sensitizer". Previous: Skin Irritation Next: Solid.

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– UN Globally Harmonised System for Classification, labelling and packaging (GHS/CLP) – REACH – Cosmetics Directive Info traditionally obtained with animal tests – Guinea pig tests, Local Lymph Node Assay (LLNA) Information on potency if a substance is a skin sensitiser often required – Intrinsic strenght to induce sensitisation

The purpose of the harmonised criteria for classification of respiratory and skin sensitisers is GHS Classification Criteria for Skin Sensitization. Little Pro on 2017-11-08 Views: . A chemical substance will be classified as a skin sensitizer if there is reliable human evidence or positive results from an appropriate animal test. A respiratory sensitiser is a substance which, when it is breathed in, can lead to occupational asthma, which is an allergic reaction in the lungs.